PSPal Surgery

Case 9 of 12Lumps34-year-old woman

Neck swelling

A model clerking. Read the left column as the record you would write; read the boxes on the right for why it is written that way.

Patient details

Name
Mrs L.K.
Age / sex
34-year-old woman
Occupation
Accountant
Marital status
Married, two children
Seen
Endocrine surgery clinic, 12:00
Clerked
Endocrine surgery clinic, 12:15
Source
Patient herself, reliable
Referred by
Family doctor

Presenting complaint

“A swelling in the front of my neck for four months.”

History of presenting complaint

Mrs L.K. was well until four months ago, when she noticed a swelling in the lower part of the front of her neck, to the right of the midline, while looking in the mirror. It has grown slowly since. It is not painful and has never suddenly enlarged. Her voice has not changed. She has no difficulty swallowing food or drink, no difficulty breathing, including when lying flat, and no noisy breathing. Her weight is steady and her appetite normal. She does not feel unusually hot or cold, does not sweat more than usual, and has no palpitations, tremor, anxiety or trouble sleeping. Her bowels are regular, and her periods are regular and unchanged. She is not more tired than usual, and her skin and hair have not changed. She has noticed no change in her eyes, no double vision and no grittiness. She has felt no other lumps in the neck. She had no radiotherapy to the head, neck or chest as a child. No one in her family has had thyroid cancer or other gland tumours, though her mother had a goitre removed that was benign. She has no bone pain, cough or weight loss. She has lived all her life in a hill village.

Past medical history

No chronic illness. No previous thyroid disease or thyroid blood tests.

Past surgical history

Two normal deliveries. No operations.

Drugs and allergies

No regular medication. No amiodarone, lithium or thyroid tablets. No known drug allergies.

Family history

Mother: thyroid operation for a benign goitre at 50. No thyroid cancer.

Social history

Does not smoke. Uses iodised salt at home.

General examination

A calm, well-looking woman, sitting comfortably and not sweating. Speech and voice normal. Weight 63 kg.

Temperature36.8 °C
Pulse76 /min, regular
Blood pressure118/74 mmHg
Respiratory rate14 /min
Oxygen saturation99% on air

Hands: warm and dry, no tremor of the outstretched fingers, no red palms, nails normal.

Eyes: no lid retraction, no lid lag, no protrusion of the eyes, movements full.

Legs: no thickening of the skin over the shins. Ankle reflexes normal, with normal relaxation.

Examination of the neck

Seated, neck slightly extended and exposed to the clavicles.

Inspection

A swelling is visible in the lower anterior neck on the right. It moves upwards when she swallows a sip of water and does not move when she puts out her tongue. No scars, no redness, no dilated veins over the neck or upper chest.

Palpation

From behind. A single nodule in the right lobe of the thyroid, 3 by 2.5 cm, firm, smooth, not tender, moving with swallowing. Its lower border can be felt above the clavicle. The left lobe and isthmus are not palpable. Trachea central. No enlarged lymph nodes in the anterior or posterior triangles or the supraclavicular fossae. Both carotid pulses felt.

Percussion and auscultation

Resonant over the upper sternum. No bruit over the gland.

Pemberton's test

Negative: no flushing of the face or distension of neck veins on raising both arms for one minute.

Other systems

Chest: clear.

Heart: first and second heart sounds normal, no murmurs.

Abdomen: soft, no masses.

Summary

Say this to the examinerMrs L.K. is a 34-year-old woman with a four-month history of a slowly growing, painless swelling in the right side of the neck, with no pressure symptoms, no symptoms of an overactive or underactive thyroid and no risk factors for thyroid cancer. On examination she is clinically euthyroid, with a 3 cm firm, smooth, solitary nodule in the right thyroid lobe that moves on swallowing, no retrosternal extension, a central trachea and no cervical lymph nodes.

Provisional diagnosis

Solitary thyroid nodule of the right lobe, clinically euthyroid. Malignancy to be excluded.

Plan

  • Thyroid stimulating hormone, with free T4 if it is abnormal. Serum calcium.
  • Ultrasound of the thyroid and neck nodes.
  • Ultrasound-guided fine needle aspiration if the ultrasound features and size call for it.
  • Isotope scan only if the thyroid stimulating hormone is suppressed.
  • Examination of the vocal cords before any operation.

Differential diagnosis of a swelling in the front of the neck

First decide whether it is thyroid. Then, for a thyroid nodule, list benign before malignant. Then give the non-thyroid causes by position.

DiagnosisPoints to it in the historyPoints to it on examinationIn this patient
Thyroid: benign
Dominant nodule of a multinodular goitreLong-standing, slow growing, family history of goitreOne nodule felt, others found on ultrasoundCommon; ultrasound decides
Colloid nodule or cystSlow growing, or sudden painful enlargement if it bleedsSmooth, firm or tensePossible
Follicular adenomaSlowly growing single noduleSmooth, firm, mobilePossible; cannot be told from cancer on cytology alone
Toxic adenomaSymptoms of an overactive thyroidFast pulse, tremor, single noduleClinically euthyroid
ThyroiditisPainful gland after a viral illness, or long-standing with underactivityTender, or firm and rubbery glandNot tender, euthyroid
Thyroid: malignant
Papillary carcinomaYoung adult, childhood neck radiation, neck nodesFirm nodule, nodes on the same sideNo nodes, but must be excluded
Follicular carcinomaMiddle age, long-standing nodule, bone painFirm noduleNeeds tissue diagnosis
Medullary carcinomaFamily history of gland tumours, diarrhoea, flushingHard nodule, nodesNo family history
Anaplastic carcinomaElderly, growth over weeks, hoarseness, noisy breathingHard, fixed massWrong age, wrong pace
LymphomaRapid growth in a gland with long-standing thyroiditisLarge firm glandNo such history
Midline, not thyroid
Thyroglossal cystChild or young adult, midline lump, sometimes infectedMoves up when the tongue is put outDoes not move with the tongue
Dermoid cystPainless midline lumpDoes not move with swallowing or the tongueMoves with swallowing
Side of the neck
Lymph nodeSore throat, fever, night sweats, weight loss, or a cancer elsewhereDoes not move with swallowing; may be multipleMoves with swallowing
Branchial cystYoung adult, smooth swelling in the upper neckAt the front edge of the muscle in the upper thirdWrong position
Carotid body tumourSlow growing lump at the angle of the jawPulsatile, moves side to side but not up and downWrong position
Model OSCE answer“This is a thyroid swelling, because it moves up on swallowing and not on protruding the tongue. It is a solitary nodule in the right lobe, and she is clinically euthyroid: her pulse is 76 and regular, with no tremor and no eye signs. There are no features to suggest malignancy: no hoarseness, no rapid growth, no neck nodes and no history of radiation. My differential is a dominant nodule of a multinodular goitre, a colloid nodule, a follicular adenoma, and thyroid cancer, most often papillary at her age. I would check thyroid stimulating hormone, arrange an ultrasound of the neck, and proceed to fine needle aspiration.”

Clinical signs related to this case

The signs you should look for in any patient with a thyroid swelling. For each one, know how to elicit it and what a positive result means.

SignHow to elicit it, or what you seeWhat it means
Is it thyroid
Moves up on swallowingGive a sip of water and watch from the frontThe swelling is attached to the larynx: thyroid, or a thyroglossal cyst
Moves up on protruding the tongueHold the lump lightly, mouth open, ask her to put out her tongueThyroglossal cyst
Signs of size and pressure
Lower border not feltFingers cannot get below the gland when she swallowsThe goitre extends behind the sternum
Dull percussion over the upper sternumPercuss the manubriumRetrosternal goitre
Pemberton's signBoth arms raised beside the head for one minute: the face flushes and neck veins fillThe thoracic inlet is blocked by a retrosternal goitre
Displaced tracheaFinger in the notch above the sternumLarge or one-sided goitre pushing the airway
Noisy breathing inHarsh sound on breathing inThe airway is narrowed: urgent
Signs of malignancy
Hard, fixed glandDoes not move well on swallowingCancer invading surrounding tissue
Hoarse voiceListen while taking the historyThe nerve to the vocal cord is involved
Enlarged neck nodesFeel along the neck on the same sideSpread, typical of papillary cancer
Absent carotid pulse (Berry's sign)Carotid pulse not felt on the side of a large goitreCancer surrounding the artery
Signs of an overactive thyroid
Fast or irregular pulseCount for a full minuteOveractivity; irregular means atrial fibrillation
Fine tremorPaper laid on the outstretched fingersOveractivity
Lid retraction and lid lagWhite of the eye visible above the iris; the lid lags behind the eye on looking downOveractivity of any cause
Protruding eyes, thickened shin skin, bruit over the glandLook from the side and from above; feel the shins; listen over the glandGraves' disease specifically
Signs of an underactive thyroid
Slow pulse, dry coarse skin, puffy faceLook and feelUnderactivity
Slow-relaxing ankle reflexThe foot returns slowly after the tendon is tappedUnderactivity

Teaching case. The patient is fictional and written to illustrate format and reasoning. Local protocols decide investigation and treatment.